Varaico: Literature-Extracted Genetic Variants

CUX2

12q24.11-q24.12 (UCSC)OMIM PanelApp GTEx

171 papers

RefSeq Summary

This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is l...

Pfam Domains

CUX1_Naa 1–114UCSCCUX1-like, N-terminal tRNA-binding arm

CUTaa 549–627UCSCCUT domain

CUTaa 892–967UCSCCUT domain

CUTaa 1043–1121UCSCCUT domain

Homeodomainaa 1169–1225UCSCHomeodomain

Gene Aliases

HGNC Name

cut like homeobox 2

HGNC Previous Symbol

CUTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015267.4

p.A1481S

c.4441G>T

Surrounding Variants

1 paper

NM_015267.4

p.A1481D

c.4442C>A

1 paper

NM_015267.4

p.E1483K

c.4447G>A

1 paper

NM_015267.4

p.R1478W

c.4432C>T

3 papers

NM_015267.4

p.V1472L

c.4414G>C

3 papers

NM_015267.4

p.V1472L

c.4414G>T

1 paper

NM_015267.4

p.R1471Q

c.4412G>A

3 papers

NM_015267.4

p.R1471*

c.4411C>T

1 paper

NM_015267.4

p.N1467K

c.4401C>A

1 paper

NM_015267.4

p.N1467K

c.4401C>G

1 paper

NM_015267.4

p.R1458Q

c.4373G>A

1 paper

NM_015267.4

p.P1453L

c.4358C>T

1 paper

NM_015267.4

p.A1439A

c.4317T>C