Varaico: Literature-Extracted Genetic Variants

Gene:CXCL8
Variant:p.L5L

CXCL8

572 papers

RefSeq Summary

The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is commonly referred to as interleukin-8 (IL-8). IL-8...

Pfam Domains

IL8aa 32–92UCSCSmall cytokines (intecrine/chemokine), interleukin-8 like

Gene Aliases

HGNC Name

C-X-C motif chemokine ligand 8

HGNC Previous Symbol

IL8

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000584.4
p.L5L
c.13C>T
Surrounding Variants
1 paper
NM_000584.4
p.K4K
c.12G>A
3 papers
NM_000584.4
p.K4N
c.12G>C
1 paper
NM_000584.4
p.L5Q
c.14T>A
1 paper
NM_000584.4
p.K4T
c.11A>C
1 paper
NM_000584.4
p.K4R
c.11A>G
1 paper
NM_000584.4
p.K4M
c.11A>T
1 paper
NM_000584.4
p.S3S
c.9C>A
1 paper
NM_000584.4
p.S3Y
c.8C>A
1 paper
NM_000584.4
p.S3C
c.8C>G
3 papers
NM_000584.4
p.S3F
c.8C>T
1 paper
NM_000584.4
p.V7M
c.19G>A
1 paper
NM_000584.4
p.T2T
c.6T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."