Varaico: Literature-Extracted Genetic Variants

Gene:CXCL8
Variant:p.L14insFs

CXCL8

572 papers

RefSeq Summary

The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is commonly referred to as interleukin-8 (IL-8). IL-8...

Pfam Domains

IL8aa 32–92UCSCSmall cytokines (intecrine/chemokine), interleukin-8 like

Gene Aliases

HGNC Name

C-X-C motif chemokine ligand 8

HGNC Previous Symbol

IL8

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000584.4
p.L14insFs
c.42dupG
Surrounding Variants
1 paper
NM_000584.4
p.L14Q
c.41T>A
1 paper
NM_000584.4
p.I15V
c.43A>G
2 papers
NM_000584.4
p.F13L
c.39C>A
1 paper
NM_000584.4
p.F13L
c.39C>G
3 papers
NM_000584.4
p.F13Y
c.38T>A
2 papers
NM_000584.4
p.I15N
c.44T>A
1 paper
NM_000584.4
p.F13L
c.37T>C
1 paper
NM_000584.4
p.I15I
c.45T>C
1 paper
NM_000584.4
p.S16P
c.46T>C
1 paper
NM_000584.4
p.S16Y
c.47C>A
1 paper
NM_000584.4
p.S16C
c.47C>G
2 papers
NM_000584.4
p.S16F
c.47C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."