Varaico: Literature-Extracted Genetic Variants

Gene:CXCL8
Variant:p.E21V

CXCL8

572 papers

RefSeq Summary

The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is commonly referred to as interleukin-8 (IL-8). IL-8...

Pfam Domains

IL8aa 32–92UCSCSmall cytokines (intecrine/chemokine), interleukin-8 like

Gene Aliases

HGNC Name

C-X-C motif chemokine ligand 8

HGNC Previous Symbol

IL8

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000584.4
p.E21V
c.62A>T
Surrounding Variants
1 paper
NM_000584.4
p.E21D
c.63A>C
1 paper
NM_000584.4
p.E21D
c.63A>T
1 paper
NM_000584.4
p.E21K
c.61G>A
2 papers
NM_000584.4
p.G22S
c.64G>A
1 paper
NM_000584.4
p.C20*
c.60T>A
2 papers
NM_000584.4
p.C20Y
c.59G>A
1 paper
NM_000584.4
p.C20R
c.58T>C
1 paper
NM_000584.4
p.L19P
c.56T>C
1 paper
NM_000584.4
p.L19insFs
c.56_57insG
1 paper
NM_000584.4
p.A18T
c.52G>A
2 papers
NM_000584.4
p.A17E
c.50C>A
2 papers
NM_000584.4
p.A17V
c.50C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."