Varaico: Literature-Extracted Genetic Variants

Gene:CXCL8
Variant:p.P46A

CXCL8

572 papers

RefSeq Summary

The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is commonly referred to as interleukin-8 (IL-8). IL-8...

Pfam Domains

IL8aa 32–92UCSCSmall cytokines (intecrine/chemokine), interleukin-8 like

Gene Aliases

HGNC Name

C-X-C motif chemokine ligand 8

HGNC Previous Symbol

IL8

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000584.4
p.P46A
c.136C>G
Surrounding Variants
1 paper
NM_000584.4
p.P46H
c.137C>A
3 papers
NM_000584.4
p.P46R
c.137C>G
2 papers
NM_000584.4
p.P46L
c.137C>T
1 paper
NM_000584.4
p.H45R
c.134A>G
1 paper
NM_000584.4
p.P46P
c.138C>T
1 paper
NM_000584.4
p.K47E
c.139A>G
1 paper
NM_000584.4
p.H45D
c.133C>G
1 paper
NM_000584.4
p.K47R
c.140A>G
1 paper
NM_000584.4
p.P43P
c.129T>C
1 paper
NM_000584.4
p.P43H
c.128C>A
1 paper
NM_000584.4
p.K42N
c.126A>C
3 papers
NM_000584.4
p.K42K
c.126A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."