Varaico: Literature-Extracted Genetic Variants

Gene:CXCR1
Variant:p.E275A

CXCR1

183 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal...

Pfam Domains

7tm_1aa 56–305UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 1

HGNC Previous Symbols

CMKAR1; IL8RA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_000634.3
p.E275A
c.824A>C
Surrounding Variants
31 papers
NM_000634.3
p.S276T
c.827G>C
1 paper
NM_000634.3
p.I273I
c.819C>T
2 papers
NM_000634.3
p.R279H
c.836G>A
1 paper
NM_000634.3
p.Q271*
c.811C>T
1 paper
NM_000634.3
p.R280C
c.838C>T
1 paper
NM_000634.3
p.T270A
c.808A>G
1 paper
NM_000634.3
p.M268L
c.802A>T
1 paper
NM_000634.3
p.M268L
c.802A>C
2 papers
NM_000634.3
p.I283F
c.847A>T
1 paper
NM_000634.3
p.G284S
c.850G>A
1 paper
NM_000634.3
p.T266A
c.796A>G
3 papers
NM_000634.3
p.D265A
c.794A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."