Varaico: Literature-Extracted Genetic Variants

Gene:CXCR1
Variant:p.K197N

CXCR1

183 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal...

Pfam Domains

7tm_1aa 56–305UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 1

HGNC Previous Symbols

CMKAR1; IL8RA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000634.3
p.K197N
c.591A>T
Surrounding Variants
1 paper
NM_000634.3
p.K197N
c.591A>C
1 paper
NM_000634.3
p.V201M
c.601G>A
1 paper
NM_000634.3
p.G192A
c.575G>C
1 paper
NM_000634.3
p.G192E
c.575G>A
1 paper
NM_000634.3
p.R203W
c.607C>T
1 paper
NM_000634.3
p.G192R
c.574G>C
2 papers
NM_000634.3
p.G192R
c.574G>A
1 paper
NM_000634.3
p.Y188*
c.564T>A
1 paper
NM_000634.3
p.F211L
c.631T>C
1 paper
NM_000634.3
p.F211L
c.633C>G
1 paper
NM_000634.3
p.F211L
c.633C>A
1 paper
NM_000634.3
p.P214L
c.641C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."