Varaico: Literature-Extracted Genetic Variants

Gene:CXCR2
Variant:p.C39S

CXCR2

226 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal...

Pfam Domains

7tm_1aa 65–314UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 2

HGNC Previous Symbol

IL8RB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001557.4
p.C39S
c.116G>C
Surrounding Variants
2 papers
NM_001557.4
p.C39S
c.115T>A
3 papers
NM_001557.4
p.A37T
c.109G>A
2 papers
NM_001557.4
p.S43P
c.127T>C
1 paper
NM_001557.4
p.E45K
c.133G>A
1 paper
NM_001557.4
p.E45*
c.133G>T
1 paper
NM_001557.4
p.L33R
c.98T>G
1 paper
NM_001557.4
p.E45D
c.135A>C
1 paper
NM_001557.4
p.E45D
c.135A>T
1 paper
NM_001557.4
p.K48Q
c.142A>C
1 paper
NM_001557.4
p.P30T
c.88C>A
1 paper
NM_001557.4
p.Y49F
c.146A>T
1 paper
NM_001557.4
p.S24N
c.71G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."