Varaico: Literature-Extracted Genetic Variants

Gene:CXCR2
Variant:p.R144H

CXCR2

226 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal...

Pfam Domains

7tm_1aa 65–314UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 2

HGNC Previous Symbol

IL8RB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_001557.4
p.R144H
c.431G>A
Surrounding Variants
3 papers
NM_001557.4
p.R144C
c.430C>T
1 paper
NM_001557.4
p.D143D
c.429C>T
1 paper
NM_001557.4
p.T152A
c.454A>G
5 papers
NM_001557.4
p.R153H
c.458G>A
1 paper
NM_001557.4
p.G133D
c.398G>A
1 paper
NM_001557.4
p.G133A
c.398G>C
1 paper
NM_001557.4
p.Y131C
c.392A>G
1 paper
NM_001557.4
p.K158*
c.472A>T
1 paper
NM_001557.4
p.F130L
c.390C>A
1 paper
NM_001557.4
p.F130L
c.390C>G
1 paper
NM_001557.4
p.K158K
c.474G>A
1 paper
NM_001557.4
p.F130L
c.388T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."