Varaico: Literature-Extracted Genetic Variants

Gene:CXCR2
Variant:p.C196S

CXCR2

226 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal...

Pfam Domains

7tm_1aa 65–314UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 2

HGNC Previous Symbol

IL8RB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001557.4
p.C196S
c.587G>C
Surrounding Variants
1 paper
NM_001557.4
p.C196S
c.586T>A
1 paper
NM_001557.4
p.Y197C
c.590A>G
1 paper
NM_001557.4
p.A195D
c.584C>A
1 paper
NM_001557.4
p.P194S
c.580C>T
1 paper
NM_001557.4
p.V192I
c.574G>A
1 paper
NM_001557.4
p.S190P
c.568T>C
1 paper
NM_001557.4
p.N203H
c.607A>C
1 paper
NM_001557.4
p.V187I
c.559G>A
1 paper
NM_001557.4
p.N206K
c.618C>A
1 paper
NM_001557.4
p.N206K
c.618C>G
2 papers
NM_001557.4
p.W207*
c.621G>A
2 papers
NM_001557.4
p.R208Q
c.623G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."