Varaico: Literature-Extracted Genetic Variants

Gene:CXCR2
Variant:p.K240_M243delFs

CXCR2

226 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal...

Pfam Domains

7tm_1aa 65–314UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 2

HGNC Previous Symbol

IL8RB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001557.4
p.K240_M243delFs
c.720_727del8
Surrounding Variants
2 papers
NM_001557.4
p.A241T
c.721G>A
1 paper
NM_001557.4
p.T237M
c.710C>T
1 paper
NM_001557.4
p.R236H
c.707G>A
4 papers
NM_001557.4
p.R236C
c.706C>T
1 paper
NM_001557.4
p.Q245H
c.735G>C
1 paper
NM_001557.4
p.Q245H
c.735G>T
2 papers
NM_001557.4
p.R248W
c.742C>T
1 paper
NM_001557.4
p.G232R
c.694G>A
1 paper
NM_001557.4
p.G232R
c.694G>C
7 papers
NM_001557.4
p.R248Q
c.743G>A
1 paper
NM_001557.4
p.C230S
c.689G>C
2 papers
NM_001557.4
p.M250L
c.748A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."