Varaico: Literature-Extracted Genetic Variants

Gene:CXCR2
Variant:p.L271L

CXCR2

226 papers

RefSeq Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal...

Pfam Domains

7tm_1aa 65–314UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 2

HGNC Previous Symbol

IL8RB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_001557.4
p.L271L
c.811C>T
Surrounding Variants
1 paper
NM_001557.4
p.P266_L269delFs
c.798_805del8
1 paper
NM_001557.4
p.L265L
c.793C>T
1 paper
NM_001557.4
p.R278R
c.832A>C
1 paper
NM_001557.4
p.R278K
c.833G>A
1 paper
NM_001557.4
p.C263S
c.788G>C
1 paper
NM_001557.4
p.C263S
c.787T>A
7 papers
NM_001557.4
p.L262L
c.786C>T
1 paper
NM_001557.4
p.L262P
c.785T>C
3 papers
NM_001557.4
p.L261L
c.781C>T
1 paper
NM_001557.4
p.I259M
c.777C>G
2 papers
NM_001557.4
p.I282T
c.845T>C
1 paper
NM_001557.4
p.Q283E
c.847C>G
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