Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003467.3

p.E343D

c.1029G>T

Surrounding Variants

1 paper

NM_003467.3

p.E343insFs

c.1028dupA

1 paper

NM_003467.3

p.S341_E343insFs

c.1022_1028dup7

2 papers

NM_003467.3

p.E343D

c.1029G>C

1 paper

NM_003467.3

p.T342_E343delFs

c.1025_1028del4

1 paper

NM_003467.3

p.S344insFs

c.1030_1031ins8

1 paper

NM_003467.3

p.S344A

c.1030T>G

1 paper

NM_003467.3

p.E343delFs

c.1028_1029delCT

1 paper

NM_003467.3

p.S344fs

c.1030_1031fs

1 paper

NM_003467.3

p.E343G

c.1028A>G

3 papers

NM_003467.3

p.E343A

c.1028A>C

39 papers

NM_003467.3

p.E343*

c.1027G>T

1 paper

NM_003467.3

p.T342insFs

c.1026dupT