Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_003467.3

p.S341fs

c.1021_1022fs

Surrounding Variants

2 papers

NM_003467.3

p.S341delFs

c.1021_1022delGA

1 paper

NM_003467.3

p.V340_S341delFs

c.1018_1022del5

1 paper

NM_003467.3

p.T342fs

c.1024_1025fs

1 paper

NM_003467.3

p.S341F

c.1022C>T

4 papers

NM_003467.3

p.S341insFs

c.1021dupT

2 papers

NM_003467.3

p.S341Y

c.1022C>A

7 papers

NM_003467.3

p.S341delFs

c.1021delA

1 paper

NM_003467.3

p.T342A

c.1024A>G

1 paper

NM_003467.3

p.T342insFs

c.1024_1025insT

2 papers

NM_003467.3

p.S341delFs

c.1023delG

1 paper

NM_003467.3

p.S339_S341delFs

c.1017_1023del7

2 papers

NM_003467.3

p.S341P

c.1021T>C