Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.L326fs

c.976_977fs

Surrounding Variants

4 papers

NM_003467.3

p.L326insFs

c.976dupC

1 paper

NM_003467.3

p.L326P

c.977T>C

1 paper

NM_003467.3

p.S325fs

c.973_974fs

1 paper

NM_003467.3

p.G323_S325delFs

c.967_974del8

2 papers

NM_003467.3

p.L326fs

c.976_977fs

3 papers

NM_003467.3

p.K327fs

c.979_980fs

2 papers

NM_003467.3

p.S325fs

c.973_974fs

2 papers

NM_003467.3

p.K327*

c.979A>T

1 paper

NM_003467.3

p.S325G

c.973A>G

1 paper

NM_003467.3

p.K327insFs

c.979_980insG

1 paper

NM_003467.3

p.S324insFs

c.972dupC

1 paper

NM_003467.3

p.S324insFs

c.970_971ins4