Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003467.3

p.L317_R322delFs

c.951_964del14

Surrounding Variants

5 papers

NM_003467.3

p.R322insFs

c.964dupA

1 paper

NM_003467.3

p.R322*

c.964A>T

1 paper

NM_003467.3

p.R322G

c.964A>G

1 paper

NM_003467.3

p.R322insFs

c.965dupG

2 papers

NM_003467.3

p.S321insFs

c.963dupC

5 papers

NM_003467.3

p.R322fs

c.964_965fs

5 papers

NM_003467.3

p.R322fs

c.964_965fs

1 paper

NM_003467.3

p.G323insFs

c.967_968ins10

1 paper

NM_003467.3

p.G323insFs

c.967_968ins4

4 papers

NM_003467.3

p.G323fs

c.967_968fs

1 paper

NM_003467.3

p.S321_R322insFs

c.963_964insTC

2 papers

NM_003467.3

p.G323V

c.968G>T