Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003467.3

p.T318delFs

c.954delG

Surrounding Variants

1 paper

NM_003467.3

p.S319A

c.955T>G

6 papers

NM_003467.3

p.S319fs

c.955_956fs

1 paper

NM_003467.3

p.S319F

c.956C>T

1 paper

NM_003467.3

p.S319C

c.956C>G

1 paper

NM_003467.3

p.L317_T318insFs

c.950_953dup4

10 papers

NM_003467.3

p.T318fs

c.952_953fs

2 papers

NM_003467.3

p.L317_T318delFs

c.950_953del4

6 papers

NM_003467.3

p.S319fs

c.955_956fs

1 paper

NM_003467.3

p.T318_S319delFs

c.952_956del5

7 papers

NM_003467.3

p.T318insFs

c.952dupA

1 paper

NM_003467.3

p.T318N

c.953C>A

1 paper

NM_003467.3

p.V320M

c.958G>A