Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003467.3

p.L317fs

c.949_950fs

Surrounding Variants

1 paper

NM_003467.3

p.L317_T318insFs

c.951_952insT

1 paper

NM_003467.3

p.L317insFs

c.949_950insC

3 papers

NM_003467.3

p.T318fs

c.952_953fs

1 paper

NM_003467.3

p.T318A

c.952A>G

3 papers

NM_003467.3

p.T318P

c.952A>C

1 paper

NM_003467.3

p.L317insFs

c.950_951dupTC

1 paper

NM_003467.3

p.T318insFs

c.952_953ins5

1 paper

NM_003467.3

p.L317F

c.949C>T

7 papers

NM_003467.3

p.T318insFs

c.952dupA

1 paper

NM_003467.3

p.T318N

c.953C>A

1 paper

NM_003467.3

p.L317_T318insFs

c.950_953dup4

10 papers

NM_003467.3

p.T318fs

c.952_953fs