Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.S312A

c.934T>G

Surrounding Variants

5 papers

NM_003467.3

p.T311fs

c.931_932fs

1 paper

NM_003467.3

p.T311insFs

c.932_933insT

1 paper

NM_003467.3

p.T311N

c.932C>A

2 papers

NM_003467.3

p.T311fs

c.931_932fs

1 paper

NM_003467.3

p.K310E

c.928A>G

1 paper

NM_003467.3

p.F309L

c.927T>G

1 paper

NM_003467.3

p.F309L

c.927T>A

1 paper

NM_003467.3

p.F309L

c.925T>C

2 papers

NM_003467.3

p.H315fs

c.943_944fs

1 paper

NM_003467.3

p.H315_A316insFs

c.945_946insA

2 papers

NM_003467.3

p.H315_A316insFs

c.945_946insC

3 papers

NM_003467.3

p.A316T

c.946G>A