Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003467.3

p.P299L

c.896C>T

Surrounding Variants

1 paper

NM_003467.3

p.P299S

c.895C>T

1 paper

NM_003467.3

p.L297L

c.889C>T

1 paper

NM_003467.3

p.Y302_A303insFs

c.906_907insTC

3 papers

NM_003467.3

p.A303T

c.907G>A

1 paper

NM_003467.3

p.H294R

c.881A>G

1 paper

NM_003467.3

p.L305V

c.913C>G

1 paper

NM_003467.3

p.F293Y

c.878T>A

1 paper

NM_003467.3

p.G306A

c.917G>C

3 papers

NM_003467.3

p.F292I

c.874T>A

2 papers

NM_003467.3

p.A307S

c.919G>T

2 papers

NM_003467.3

p.A291T

c.871G>A

1 paper

NM_003467.3

p.L290P

c.869T>C