Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.L246P

c.737T>C

Surrounding Variants

1 paper

NM_003467.3

p.A247T

c.739G>A

1 paper

NM_003467.3

p.A247D

c.740C>A

1 paper

NM_003467.3

p.I243_A247delFs

c.728_740del13

1 paper

NM_003467.3

p.L244H

c.731T>A

1 paper

NM_003467.3

p.I243T

c.728T>C

1 paper

NM_003467.3

p.A250T

c.748G>A

1 paper

NM_003467.3

p.V242V

c.726C>T

3 papers

NM_003467.3

p.V242A

c.725T>C

1 paper

NM_003467.3

p.V242D

c.725T>A

1 paper

NM_003467.3

p.V242F

c.724G>T

1 paper

NM_003467.3

p.C251S

c.751T>A

1 paper

NM_003467.3

p.C251S

c.752G>C