Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.A141S

c.421G>T

Surrounding Variants

3 papers

NM_003467.3

p.A141T

c.421G>A

1 paper

NM_003467.3

p.H140Y

c.418C>T

1 paper

NM_003467.3

p.L136_A141del6

c.406_422del18

1 paper

NM_003467.3

p.A128_H140del13

c.382_419del39

1 paper

NM_003467.3

p.V139D

c.416T>A

1 paper

NM_003467.3

p.T142T

c.426C>T

1 paper

NM_003467.3

p.V139I

c.415G>A

8 papers

NM_003467.3

p.I138I

c.414C>T

1 paper

NM_003467.3

p.N143I

c.428A>T

1 paper

NM_003467.3

p.N143N

c.429C>T

1 paper

NM_003467.3

p.S144C

c.430A>T

1 paper

NM_003467.3

p.S144R

c.430A>C