Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.Y116Y

c.348C>T

Surrounding Variants

2 papers

NM_003467.3

p.T117A

c.349A>G

2 papers

NM_003467.3

p.V118I

c.352G>A

1 paper

NM_003467.3

p.N119H

c.355A>C

1 paper

NM_003467.3

p.V114I

c.340G>A

6 papers

NM_003467.3

p.N119S

c.356A>G

1 paper

NM_003467.3

p.N119K

c.357C>G

1 paper

NM_003467.3

p.N119K

c.357C>A

1 paper

NM_003467.3

p.H113R

c.338A>G

1 paper

NM_003467.3

p.H113P

c.338A>C

2 papers

NM_003467.3

p.V112G

c.335T>G

1 paper

NM_003467.3

p.V112F

c.334G>T

1 paper

NM_003467.3

p.V112L

c.334G>C