Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.K110fs

c.328_329fs

Surrounding Variants

1 paper

NM_003467.3

p.K110*

c.328A>T

1 paper

NM_003467.3

p.C109S

c.326G>C

1 paper

NM_003467.3

p.C109S

c.325T>A

1 paper

NM_003467.3

p.L108R

c.323T>G

1 paper

NM_003467.3

p.V112F

c.334G>T

1 paper

NM_003467.3

p.V112L

c.334G>C

2 papers

NM_003467.3

p.V112G

c.335T>G

2 papers

NM_003467.3

p.F107L

c.321C>G

3 papers

NM_003467.3

p.F107L

c.321C>A

2 papers

NM_003467.3

p.F107L

c.319T>C

1 paper

NM_003467.3

p.H113R

c.338A>G

1 paper

NM_003467.3

p.H113P

c.338A>C