Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.Y76C

c.227A>G

Surrounding Variants

1 paper

NM_003467.3

p.Y76N

c.226T>A

1 paper

NM_003467.3

p.Y76*

c.228C>A

1 paper

NM_003467.3

p.R77R

c.229A>C

2 papers

NM_003467.3

p.R77K

c.230G>A

1 paper

NM_003467.3

p.K75M

c.224A>T

1 paper

NM_003467.3

p.D74N

c.220G>A

1 paper

NM_003467.3

p.T73T

c.219G>A

2 papers

NM_003467.3

p.T73M

c.218C>T

2 papers

NM_003467.3

p.H79P

c.236A>C

1 paper

NM_003467.3

p.T73A

c.217A>G

1 paper

NM_003467.3

p.G64_M72delFs

c.191_215del25

1 paper

NM_003467.3

p.L80M

c.238C>A