Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.I47_F49delFs

c.141_147del7

Surrounding Variants

1 paper

NM_003467.3

p.I47_F49del0

c.141_146del6

1 paper

NM_003467.3

p.I47_F49del3

c.139_146del9

1 paper

NM_003467.3

p.I48_L50del3

c.142_149del9

1 paper

NM_003467.3

p.I44_T51delFs

c.130_151del22

2 papers

NM_003467.3

p.T51T

c.153T>A

1 paper

NM_003467.3

p.S46_I47del0

c.136_141del6

1 paper

NM_003467.3

p.T43_I47delFs

c.128_140del13

1 paper

NM_003467.3

p.I53V

c.157A>G

8 papers

NM_003467.3

p.I53L

c.157A>C

6 papers

NM_003467.3

p.S46S

c.138C>T

1 paper

NM_003467.3

p.Y45_I53delFs

c.134_158del25

1 paper

NM_003467.3

p.S46F

c.137C>T