Varaico: Literature-Extracted Genetic Variants

Gene:CYSLTR2
Variant:p.I152L

CYSLTR2

141 papers

RefSeq Summary

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the ...

Pfam Domains

7tm_1aa 55–305UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

cysteinyl leukotriene receptor 2

HGNC Alias Symbols

CysLT(2); CYSLT2R

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001308476.3
p.I152L
c.454A>C
Surrounding Variants
6 papers
NM_001308476.3
p.S154N
c.461G>A
1 paper
NM_001308476.3
p.H148Q
c.444T>A
1 paper
NM_001308476.3
p.H148Q
c.444T>G
2 papers
NM_001308476.3
p.W156R
c.466T>C
1 paper
NM_001308476.3
p.R145W
c.433C>T
4 papers
NM_001308476.3
p.F137S
c.410T>C
2 papers
NM_001308476.3
p.R136H
c.407G>A
1 paper
NM_001308476.3
p.R136P
c.407G>C
2 papers
NM_001308476.3
p.R136C
c.406C>T
1 paper
NM_001308476.3
p.V135L
c.403G>C
1 paper
NM_001308476.3
p.V135L
c.403G>T
1 paper
NM_001308476.3
p.S133N
c.398G>A
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