Varaico: Literature-Extracted Genetic Variants

DAB2IP

122 papers

RefSeq Summary

DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15...

Pfam Domains

PH_RASGAPaa 70–201UCSCPH domain-like

C2aa 213–313UCSCC2 domain

RasGAPaa 392–469UCSCGTPase-activator protein for Ras-like GTPase

Gene Aliases

HGNC Name

DAB2 interacting protein

HGNC Alias Symbols

AF9Q34; DIP1/2; KIAA1743; AIP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001395010.1

p.G774A

c.2321G>C

Surrounding Variants

1 paper

NM_001395010.1

p.A776_V782del7

c.2326_2345del21

1 paper

NM_001395010.1

p.V769_P771del3

c.2305_2312del9

1 paper

NM_001395010.1

p.W785G

c.2353T>G

1 paper

NM_001395010.1

p.A740P

c.2218G>C

1 paper

NM_138709.2

p.G694D

c.2081G>A

2 papers

NM_001395010.1

p.L823delFs

c.2467delT

1 paper

NM_001395010.1

p.P723A

c.2167C>G

1 paper

NM_001395010.1

p.V832M

c.2494G>A

1 paper

NM_001395010.1

p.G853_S855del3

c.2557_2564del9

1 paper

NM_001395010.1

p.A870T

c.2608G>A

1 paper

NM_001395010.1

p.E898delFs

c.2693delA

1 paper

NM_001395010.1

p.E898_K899insFs

c.2694_2695insC