DDB1 and CUL4 associated factor 6

IQWD1

PC326

IQ motif and WD repeats 1

DDB1- and CUL4-associated factor 6

Androgen receptor complex-associated protein

IQ motif and WD repeat-containing protein 1

Nuclear receptor interaction protein

ARCAP

NRIP

The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017].

Varaico: Literature-Extracted Genetic Variants

DCAF6

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol