Varaico: Literature-Extracted Genetic Variants

DCAF8

57 papers

RefSeq Summary

This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene. [...

Pfam Domains

WD40aa 183–221UCSCWD domain, G-beta repeat

WD40aa 422–463UCSCWD domain, G-beta repeat

WD40aa 467–506UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

DDB1 and CUL4 associated factor 8

HGNC Previous Symbol

WDR42A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_015726.4

p.P296H

c.887C>A

Surrounding Variants

1 paper

NM_015726.4

p.R314K

c.941G>A

3 papers

NM_015726.4

p.R317C

c.949C>T

1 paper

NM_015726.4

p.R317H

c.950G>A

1 paper

NM_015726.4

p.S320Splc

c.959+1G>A

2 papers

NM_015726.4

p.A269D

c.806C>A

1 paper

NM_015726.4

p.S268A

c.802T>G

1 paper

NM_015726.4

p.R263_E266del4

c.787_797del12

1 paper

NM_015726.4

p.E266Q

c.796G>C

2 papers

NM_015726.4

p.A257A

c.771C>T

1 paper

NM_015726.4

p.C256F

c.767G>T

1 paper

NM_015726.4

p.A254T

c.760G>A

1 paper

NM_015726.4

p.D230Y

c.688G>T