Varaico: Literature-Extracted Genetic Variants

DCTN1

606 papers

RefSeq Summary

This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dyn...

Pfam Domains

CAP_GLYaa 29–94UCSCCAP-Gly domain

Dynactinaa 523–805UCSCDynein associated protein

DUF8221aa 943–1034UCSCDomain of unknown function (DUF8221)

Gene Aliases

HGNC Name

dynactin subunit 1

HGNC Previous Name

dynactin 1 (p150, Glued (Drosophila) homolog)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004082.5

p.I1277F

c.3829A>T

Surrounding Variants

1 paper

NM_004082.5

p.L1276V

c.3826C>G

10 papers

NM_004082.5

p.R1275C

c.3823C>T

8 papers

NM_004082.5

p.H1270Q

c.3810C>G

8 papers

NM_004082.5

p.H1270Q

c.3810C>A

1 paper

NM_004082.5

p.Q1268R

c.3803A>G

2 papers

NM_004082.5

p.E1267Q

c.3799G>C

3 papers

NM_004082.5

p.E1267K

c.3799G>A

1 paper

NM_004082.5

p.Q1266K

c.3796C>A

1 paper

NM_004082.5

p.V1263G

c.3788T>G

5 papers

NM_004082.5

p.R1261Q

c.3782G>A

1 paper

NM_004082.5

p.F1256C

c.3767T>G

4 papers

NM_004082.5

p.A1254S

c.3760G>T