Varaico: Literature-Extracted Genetic Variants

DDR1

352 papers

RefSeq Summary

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The pr...

Pfam Domains

F5_F8_type_Caa 46–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 610–905UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 1

HGNC Previous Symbols

NTRK4; PTK3A; NEP; CAK; EDDR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001297654.2

p.P147H

c.440C>A

Surrounding Variants

1 paper

NM_001297654.2

p.P147T

c.439C>A

1 paper

NM_001297654.2

p.D146G

c.437A>G

1 paper

NM_001297654.2

p.D146V

c.437A>T

1 paper

NM_001297654.2

p.G143D

c.428G>A

1 paper

NM_001297654.2

p.D154A

c.461A>C

1 paper

NM_001297654.2

p.P157H

c.470C>A

1 paper

NM_001297654.2

p.P158L

c.473C>T

1 paper

NM_001297654.2

p.P168S

c.502C>T

1 paper

NM_001297654.2

p.P168L

c.503C>T

1 paper

NM_001297654.2

p.R169R

c.507G>C

1 paper

NM_001297654.2

p.A170D

c.509C>A

1 paper

NM_001297654.2

p.R172W

c.514C>T