Varaico: Literature-Extracted Genetic Variants

DDR1

352 papers

RefSeq Summary

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The pr...

Pfam Domains

F5_F8_type_Caa 46–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 610–905UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 1

HGNC Previous Symbols

NTRK4; PTK3A; NEP; CAK; EDDR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001297654.2

p.G217A

c.650G>C

Surrounding Variants

1 paper

NM_001297654.2

p.G221G

c.663C>T

2 papers

NM_001297654.2

p.S213A

c.637T>G

1 paper

NM_001297654.2

p.G222R

c.664G>A

1 paper

NM_001297654.2

p.A207P

c.619G>C

1 paper

NM_001297654.2

p.V198A

c.593T>C

1 paper

NM_001297654.2

p.P197L

c.590C>T

1 paper

NM_001297654.2

p.L186H

c.557T>A

1 paper

NM_001297654.2

p.G184S

c.550G>A

1 paper

NM_001297654.2

p.E181Q

c.541G>C

1 paper

NM_001297654.2

p.V180A

c.539T>C

1 paper

NM_001297654.2

p.R179W

c.535C>T

1 paper

NM_001297654.2

p.L178M

c.532C>A