Varaico: Literature-Extracted Genetic Variants

DDR1

352 papers

RefSeq Summary

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The pr...

Pfam Domains

F5_F8_type_Caa 46–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 610–905UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 1

HGNC Previous Symbols

NTRK4; PTK3A; NEP; CAK; EDDR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001297654.2

p.A279T

c.835G>A

Surrounding Variants

1 paper

NM_001297654.2

p.R278K

c.833G>A

1 paper

NM_001297654.2

p.A282T

c.844G>A

1 paper

NM_001297654.2

p.E271A

c.812A>C

1 paper

NM_001297654.2

p.M270I

c.810G>A

1 paper

NM_001297654.2

p.M270I

c.810G>C

1 paper

NM_001297654.2

p.V268M

c.802G>A

1 paper

NM_001297654.2

p.W258*

c.774G>A

1 paper

NM_001297654.2

p.W258*

c.773G>A

1 paper

NM_001297654.2

p.Y255*

c.765T>A

2 papers

NM_001297654.2

p.Y253F

c.758A>T

2 papers

NM_001297654.2

p.Y253H

c.757T>C

1 paper

NM_001297654.2

p.P251L

c.752C>T