Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.D69Y

c.205G>T

Surrounding Variants

1 paper

NM_006182.4

p.D69A

c.206A>C

1 paper

NM_006182.4

p.D69V

c.206A>T

1 paper

NM_006182.4

p.G68V

c.203G>T

2 papers

NM_006182.4

p.G68W

c.202G>T

1 paper

NM_006182.4

p.A71T

c.211G>A

1 paper

NM_006182.4

p.A71S

c.211G>T

1 paper

NM_006182.4

p.E66D

c.198A>T

1 paper

NM_006182.4

p.A71_W72insFs

c.213_214insT

1 paper

NM_006182.4

p.W72R

c.214T>C

1 paper

NM_006182.4

p.W72L

c.215G>T

2 papers

NM_006182.4

p.S65*

c.194C>A

2 papers

NM_006182.4

p.S65*

c.194C>G