Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.L83fs

c.247_248fs

Surrounding Variants

1 paper

NM_006182.4

p.D82_L83delFs

c.246_247delCC

1 paper

NM_006182.4

p.D82Y

c.244G>T

1 paper

NM_006182.4

p.D81E

c.243T>A

1 paper

NM_006182.4

p.D81D

c.243T>C

1 paper

NM_006182.4

p.D81E

c.243T>G

8 papers

NM_006182.4

p.E85Q

c.253G>C

1 paper

NM_006182.4

p.P80A

c.238C>G

1 paper

NM_006182.4

p.E79G

c.236A>G

1 paper

NM_006182.4

p.L87M

c.259C>A

1 paper

NM_006182.4

p.E79K

c.235G>A

1 paper

NM_006182.4

p.V78A

c.233T>C

1 paper

NM_006182.4

p.P77Q

c.230C>A