Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.L94I

c.280C>A

Surrounding Variants

2 papers

NM_006182.4

p.L94F

c.280C>T

2 papers

NM_006182.4

p.T93I

c.278C>T

1 paper

NM_006182.4

p.T93_L94insP

c.277_281ins3

1 paper

NM_006182.4

p.H95N

c.283C>A

1 paper

NM_006182.4

p.H92Y

c.274C>T

1 paper

NM_006182.4

p.F96fs

c.286_287fs

1 paper

NM_006182.4

p.L91_L94del0

c.271_282del12

1 paper

NM_006182.4

p.I97M

c.291C>G

1 paper

NM_006182.4

p.T98A

c.292A>G

2 papers

NM_006182.4

p.T98I

c.293C>T

1 paper

NM_006182.4

p.L99Q

c.296T>A

2 papers

NM_006182.4

p.V100M

c.298G>A