Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

12 papers

NM_006182.4

p.R105C

c.313C>T

Surrounding Variants

11 papers

NM_006182.4

p.R105S

c.313C>A

8 papers

NM_006182.4

p.R105H

c.314G>A

2 papers

NM_006182.4

p.G104R

c.310G>A

2 papers

NM_006182.4

p.G104R

c.310G>C

2 papers

NM_006182.4

p.G104W

c.310G>T

1 paper

NM_006182.4

p.Q103H

c.309G>C

1 paper

NM_006182.4

p.Q103H

c.309G>T

1 paper

NM_006182.4

p.Q103K

c.307C>A

3 papers

NM_006182.4

p.Q103*

c.307C>T

1 paper

NM_006182.4

p.A107S

c.319G>T

1 paper

NM_006182.4

p.A107V

c.320C>T

1 paper

NM_006182.4

p.T102N

c.305C>A