Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.Y122C

c.365A>G

Surrounding Variants

1 paper

NM_006182.4

p.S123I

c.368G>T

4 papers

NM_006182.4

p.I120M

c.360C>G

8 papers

NM_006182.4

p.R124W

c.370C>T

3 papers

NM_006182.4

p.R124Q

c.371G>A

2 papers

NM_006182.4

p.R124L

c.371G>T

1 paper

NM_006182.4

p.D125del1

c.373_374delGAT

2 papers

NM_006182.4

p.D125N

c.373G>A

5 papers

NM_006182.4

p.D125Y

c.373G>T

1 paper

NM_006182.4

p.G126V

c.377G>T

2 papers

NM_006182.4

p.M117I

c.351G>A

2 papers

NM_006182.4

p.M117I

c.351G>C

2 papers

NM_006182.4

p.M117I

c.351G>T