Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.W129R

c.385T>C

Surrounding Variants

3 papers

NM_006182.4

p.R128H

c.383G>A

1 paper

NM_006182.4

p.R128S

c.382C>A

1 paper

NM_006182.4

p.R128G

c.382C>G

3 papers

NM_006182.4

p.R128C

c.382C>T

1 paper

NM_006182.4

p.S131Y

c.392C>A

2 papers

NM_006182.4

p.S131C

c.392C>G

1 paper

NM_006182.4

p.G126V

c.377G>T

1 paper

NM_006182.4

p.W132*

c.395G>A

1 paper

NM_006182.4

p.W132L

c.395G>T

1 paper

NM_006182.4

p.W132*

c.396G>A

1 paper

NM_006182.4

p.R133G

c.397C>G

1 paper

NM_006182.4

p.R133W

c.397C>T