Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.V236M

c.706G>A

Surrounding Variants

1 paper

NM_006182.4

p.G235V

c.704G>T

1 paper

NM_006182.4

p.G235S

c.703G>A

1 paper

NM_006182.4

p.G235C

c.703G>T

1 paper

NM_006182.4

p.S237F

c.710C>T

2 papers

NM_006182.4

p.D234N

c.700G>A

4 papers

NM_006182.4

p.T233T

c.699C>T

1 paper

NM_006182.4

p.G238D

c.713G>A

1 paper

NM_006182.4

p.T233I

c.698C>T

1 paper

NM_006182.4

p.L239M

c.715C>A

1 paper

NM_006182.4

p.L232F

c.696G>C

1 paper

NM_006182.4

p.L232F

c.696G>T

2 papers

NM_006182.4

p.L239P

c.716T>C