Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.Y256C

c.767A>G

Surrounding Variants

1 paper

NM_006182.4

p.V257V

c.771G>T

1 paper

NM_006182.4

p.Y254H

c.760T>C

1 paper

NM_006182.4

p.W259R

c.775T>A

1 paper

NM_006182.4

p.W259R

c.775T>C

1 paper

NM_006182.4

p.G253D

c.758G>A

2 papers

NM_006182.4

p.G253S

c.757G>A

9 papers

NM_006182.4

p.G253C

c.757G>T

1 paper

NM_006182.4

p.P252P

c.756C>A

1 paper

NM_006182.4

p.R260W

c.778C>T

1 paper

NM_006182.4

p.P252L

c.755C>T

1 paper

NM_006182.4

p.R260Q

c.779G>A

1 paper

NM_006182.4

p.W251*

c.753G>A