Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.N266S

c.797A>G

Surrounding Variants

1 paper

NM_006182.4

p.T265T

c.795C>A

1 paper

NM_006182.4

p.A264V

c.791C>T

1 paper

NM_006182.4

p.E270*

c.808G>T

1 paper

NM_006182.4

p.E262K

c.784G>A

1 paper

NM_006182.4

p.E262*

c.784G>T

1 paper

NM_006182.4

p.I271N

c.812T>A

1 paper

NM_006182.4

p.R260Q

c.779G>A

1 paper

NM_006182.4

p.R260W

c.778C>T

1 paper

NM_006182.4

p.W259R

c.775T>A

1 paper

NM_006182.4

p.W259R

c.775T>C

1 paper

NM_006182.4

p.V257V

c.771G>T

1 paper

NM_006182.4

p.Y256C

c.767A>G