Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006182.4

p.S319A

c.955T>G

Surrounding Variants

1 paper

NM_006182.4

p.I318N

c.953T>A

1 paper

NM_006182.4

p.I318fs

c.952_953fs

1 paper

NM_006182.4

p.A317_I318Fs

c.950_952delinsCTFs

1 paper

NM_006182.4

p.F320S

c.959T>C

1 paper

NM_006182.4

p.P321_L322delins

c.962_964delinsTCT

2 papers

NM_006182.4

p.L322F

c.964C>T

1 paper

NM_006182.4

p.L322P

c.965T>C

4 papers

NM_006182.4

p.L324P

c.971T>C

12 papers

NM_006182.4

p.S311N

c.932G>A

1 paper

NM_006182.4

p.S311G

c.931A>G

3 papers

NM_006182.4

p.V327I

c.979G>A

1 paper

NM_006182.4

p.R307L

c.920G>T