Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006182.4

p.V336L

c.1006G>T

Surrounding Variants

2 papers

NM_006182.4

p.V336L

c.1006G>C

2 papers

NM_006182.4

p.T335_V336delins

c.1005_1006delinsTT

3 papers

NM_006182.4

p.L338F

c.1012C>T

1 paper

NM_006182.4

p.F333S

c.998T>C

1 paper

NM_006182.4

p.H339R

c.1016A>G

1 paper

NM_006182.4

p.R332Q

c.995G>A

1 paper

NM_006182.4

p.H340D

c.1018C>G

3 papers

NM_006182.4

p.R332W

c.994C>T

1 paper

NM_006182.4

p.R341Q

c.1022G>A

1 paper

NM_006182.4

p.M342K

c.1025T>A

3 papers

NM_006182.4

p.V327I

c.979G>A

4 papers

NM_006182.4

p.L324P

c.971T>C