Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.Y350*

c.1050C>G

Surrounding Variants

1 paper

NM_006182.4

p.Y350*

c.1050C>A

1 paper

NM_006182.4

p.C348W

c.1044T>G

3 papers

NM_006182.4

p.A353V

c.1058C>T

1 paper

NM_006182.4

p.T355del1

c.1063_1064delACC

3 papers

NM_006182.4

p.M357I

c.1071G>A

3 papers

NM_006182.4

p.M357I

c.1071G>C

3 papers

NM_006182.4

p.M357I

c.1071G>T

1 paper

NM_006182.4

p.M342K

c.1025T>A

1 paper

NM_006182.4

p.F359L

c.1075T>C

1 paper

NM_006182.4

p.F359V

c.1075T>G

1 paper

NM_006182.4

p.F359L

c.1077C>A

1 paper

NM_006182.4

p.F359L

c.1077C>G