Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.D367Splc

c.1099+3A>T

Surrounding Variants

1 paper

NM_006182.4

p.D367Splc

c.1099+1G>A

1 paper

NM_006182.4

p.S366*

c.1097C>A

1 paper

NM_006182.4

p.S366*

c.1097C>G

2 papers

NM_006182.4

p.S366L

c.1097C>T

1 paper

NM_006182.4

p.S366A

c.1096T>G

1 paper

NM_006182.4

p.Q365R

c.1094A>G

1 paper

NM_006182.4

p.F364L

c.1092C>A

1 paper

NM_006182.4

p.F364L

c.1092C>G

1 paper

NM_006182.4

p.F364L

c.1090T>C

1 paper

NM_006182.4

p.E361D

c.1083G>C

1 paper

NM_006182.4

p.E361D

c.1083G>T

1 paper

NM_006182.4

p.F359L

c.1077C>A