Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

18 papers

NM_006182.4

p.M441I

c.1323G>A

Surrounding Variants

18 papers

NM_006182.4

p.M441I

c.1323G>C

18 papers

NM_006182.4

p.M441I

c.1323G>T

1 paper

NM_006182.4

p.T442S

c.1324A>T

1 paper

NM_006182.4

p.T442I

c.1325C>T

1 paper

NM_006182.4

p.E440*

c.1318G>T

1 paper

NM_006182.4

p.L445F

c.1333C>T

1 paper

NM_006182.4

p.S446S

c.1338C>A

1 paper

NM_006182.4

p.L447M

c.1339C>A

1 paper

NM_006182.4

p.P448S

c.1342C>T

1 paper

NM_006182.4

p.R434R

c.1302G>T

1 paper

NM_006182.4

p.S449G

c.1345A>G

1 paper

NM_006182.4

p.R434L

c.1301G>T