Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006182.4

p.G502Splc

c.1504+1G>A

Surrounding Variants

1 paper

NM_006182.4

p.S501*

c.1502C>A

1 paper

NM_006182.4

p.S501*

c.1502C>G

1 paper

NM_006182.4

p.G502Splc

c.1504+6G>A

1 paper

NM_006182.4

p.E499*

c.1495G>T

1 paper

NM_006182.4

p.G502Splc

c.1504+11T>C

1 paper

NM_006182.4

p.G497V

c.1490G>T

1 paper

NM_006182.4

p.G497W

c.1489G>T

1 paper

NM_006182.4

p.G502Splc

c.1504+19G>A

1 paper

NM_006182.4

p.A495_P496ins2

c.1485_1486ins6

1 paper

NM_006182.4

p.A495insFs

c.1484_1485insAA

1 paper

NM_006182.4

p.A495ins1

c.1484_1485insAAG

6 papers

NM_006182.4

p.G502Splc

c.1504+25T>C