Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.R619Splc

c.1857-1G>T

Surrounding Variants

1 paper

NM_006182.4

p.R619Splc

c.1857-4C>A

1 paper

NM_006182.4

p.R619Splc

c.1857-5C>A

1 paper

NM_006182.4

p.R619Splc

c.1857-6C>T

1 paper

NM_006182.4

p.D621Y

c.1861G>T

1 paper

NM_006182.4

p.D621V

c.1862A>T

1 paper

NM_006182.4

p.R619Splc

c.1857-9C>T

1 paper

NM_006182.4

p.L623F

c.1867C>T

1 paper

NM_006182.4

p.K624N

c.1872G>C

1 paper

NM_006182.4

p.E625D

c.1875G>C

1 paper

NM_006182.4

p.E625D

c.1875G>T

1 paper

NM_006182.4

p.I626T

c.1877T>C

2 papers

NM_006182.4

p.M629V

c.1885A>G